Sodium thiopental (Sodium Pentothal) vials


UPAC: 5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione

Synonyms: Bomathal, Nesdonal, Penthiobarbital, Pentothal, Pentothal Sodico, Sodipental, Thiomebumal, Thionembutal, Thiopental, Thiopental Nycomed, Thiopental Sodium, Thiopentobarbital, Thiopentobarbitone, Thiopentobarbituric acid, Thiopentone, Tiobarbital Braun, Trapanal

CAS#: 71-73-8 (Sodium Salt), 76-75-5 (Free Acid)

Molecular Mass: 264.32 g/mol

Molecular Formula: C11H17N2NaO2S

Form: Liquid

Administration: IV (Intravenous), Oral, Rectal

Storage: Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at 20-25°C (68-77°F), however, brief excursions are permitted between 15-30°C (59-86°F).

Each Vial contains 500 mg of Thiopental Sodium.

Sodium thiopental, also known as Sodium Pentothal (or Truth Serum) is the sodium salt form of thiopental, an ultrashort-acting barbituric acid derivative, with anesthetic activity.

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What is Sodium Thiopental (Sodium Pentothal)?
Sodium Thiopental is a barbiturate (bar-BIT-chur-ate) that is administered intravenously to involve general sedation or to create short-term complete sedation. It is also used for penetration and to control seizure conditions. It has been used in neurosurgical patients to reduce dilated intracranial weight. It does not create any excitation, but has helpless pain-relieving properties and muscle-relaxing properties. It has been shown that small doses are against pain relief and lower the pain threshold. Thiopental Sodium facilitates movement in your mind and sensory system.

1. Sedation

Sodium thiopental is a super-short-acting barbiturate and has usually been used during the general sedation acceptance period. Its use has generally been replaced by propofol, but is known as an acceptance specialist for rapid succession intubation and in obstetrics.

In veterinary medicine, sodium thiopental is used to encourage sedation in creatures. Since it is rearranged to fat, certain slim types of dogs, for example, sighted dogs will have drawn recuperations from sodium thiopental due to their absence of muscle versus fat and their fat weight. After that, large creatures will have quick cures, yet it will take a while before it is completely taken out (used) from their bodies.

2. Restoratively induced trance-like state

Regardless of acceptance of sedation, sodium thiopental was generally used to initiate clinical trance states. It has now been replaced by medications, for example, propofol in light of the fact that their belongings wear out faster than thiopental. Patients with dilated minds who cause the height of the intracranial weight, either optional for injury or after a medical procedure, may benefit from this medication.

3. Epileptic status

In epileptics with strong status, thiopental can be used to end a seizure.

Intentional eradication

Sodium thiopental is used intravenously for the causes of homicide. In both Belgium and the Netherlands, where dynamic killing is permitted by law, the standard convention proposes sodium thiopental as the ideal operator to induce unconsciousness, drawn by pancuronium bromide to calm muscles and stop relaxing.

The intravenous organization is the most solid and rapid approach to achieving intentional eradication. The decline is rapid. A state of extreme lethargy only occurs when intravenously organizing 20 mg / kg of thiopental sodium (Nesdonal) in a small volume (10 ml of physiological saline). At this time, a triple dose of a non-depolarizing neuromuscular barrier drug is given, for example, 20 mg pancuronium bromide (Pavulon) or 20 mg vecuronium bromide (Norcuron). The muscle relaxant should be offered intravenously to guarantee ideal availability, but pancuronium bromide can be controlled intramuscularly at an extended dose level of 40 mg.

5. Lethal infusion

In addition to pancuronium bromide and potassium chloride, thiopental is used under 34 conditions in the United States to execute prisoners by lethal infusion. A large portion is given to guarantee rapid loss of knowledge. Despite the fact that death typically occurs within ten minutes after the start of the infusion cycle, some have been known to take longer.

6. Truth Serum

Thiopental (Pentothal) is still used on certain spots as a reality serum to weaken the determination of a subject and make them more comfortable to print. [19] The barbiturates as a class reject higher cortical minds working. A few therapists speculate that since lying is more exciting than getting clean, hiding the higher cortical capacities can lead to the revelation of reality. The medicine will generally make the subjects talkative and pleasant with the investigators; nevertheless, the reliability of recordings made during thiopental is deficient.

7. Psychiatry

Specialists have used Sodium thiopental (Sodium Pentothal) to desensitize patients with fear and to “encourage the review of unbearable swollen memories.”


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